Search Count: 21
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Rat Comt In Complex With Inhibitor
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2018-10-10 Classification: TRANSFERASE Ligands: MG, SAH, FGQ, DMS |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2018-10-10
Ligands: MG, SAH, FGQ, DMS
 |
Pde10 Complexed With6-Chloro-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]-5-Methyl-2-[2-(2-Pyridyl)Ethoxy]Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2015-12-02 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4PX, 4Y1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-02
Ligands: ZN, MG, 4PX, 4Y1
 |
Pde10 Complexed With 6-Chloro-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]-5-Methyl-2-[3-(2-Quinolyl)Propoxy]Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2015-10-07 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4PX, 4XU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-07
Ligands: ZN, MG, 4PX, 4XU
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Pde10 Complexed With 4,6-Dichloro-2-Cyclopropyl-5-Methyl-Pyrimidine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4XS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4XS
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Pde10 Complexed With 6-Chloro-2-Cyclopropyl-5-Methyl-Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.56 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4XV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4XV
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Pde10 Complexed With 6-Chloro-2-Cyclopropyl-5-Methyl-N-Propyl-Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4XY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4XY
 |
Pde10 Complexed With 6-Chloro-2-Cyclopropyl-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]-5-Methyl-Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4Y2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4Y2
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Bace1 In Complex With 4-(Cyclohexylamino)-1-(3-Fluorophenyl)-8-(3-Isopropoxybenzyl)-1,3,8-Triazaspiro[4.5]Dec-3-En-2-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2015-08-05 Classification: Hydrolase/hydrolase inhibitor Ligands: 4QA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-05
Ligands: 4QA
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Bace1 In Complex With 8-(3-((1-Aminopropan-2-Yl)Oxy)Benzyl)-4-(Cyclohexylamino)-1-(3-Fluorophenyl)-1,3,8-Triazaspiro[4.5]Dec-3-En-2-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2015-08-05 Classification: Hydrolase/Hydrolase inhibitor Ligands: 4QD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-05
Ligands: 4QD
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Bace1 In Complex With 8-Benzyl-4-(Cyclohexylamino)-1-(3-Fluorophenyl)-7-Methyl-1,3,8-Triazaspiro[4.5]Dec-3-En-2-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2015-08-05 Classification: Hydrolase/hydrolase inhibitor Ligands: 4QF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-05
Ligands: 4QF
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Synthesis And Evaluation Of Heterocyclic Catechol Mimics As Inhibitors Of Catechol-O-Methyltransferase (Comt): Structure With Cmpd18 (1-(Biphenyl-3-Yl)-3-Hydroxypyridin-4(1H)-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2015-04-15 Classification: transferase/transferase inhibitor Ligands: 43G, MG, SAM, MES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-15
Ligands: 43G, MG, SAM, MES
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Synthesis And Evaluation Of Heterocyclic Catechol Mimics As Inhibitors Of Catechol-O-Methyltransferase (Comt): Structure With Cmpd32 ([1-(Biphenyl-3-Yl)-5-Hydroxy-4-Oxo-1,4-Dihydropyridin-3-Yl]Boronic Acid)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2015-04-15 Classification: transferase/transferase inhibitor Ligands: 43H, MG, SAM, MES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-15
Ligands: 43H, MG, SAM, MES
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Synthesis And Evaluation Of Heterocyclic Catechol Mimics As Inhibitors Of Catechol-O-Methyltransferase (Comt): Structure With Cmpd27B
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2015-04-15 Classification: transferase/transferase inhibitor Ligands: 43J, MG, SAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-15
Ligands: 43J, MG, SAM
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Crystal Structure Of Human Beta Secretase Complexed With Spiropiperdine Iminohydantoin Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2009-01-20 Classification: HYDROLASE Ligands: SII |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-01-20
Ligands: SII
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Crystal Structure Of Human Beta Secretase Complexed With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2007-08-14 Classification: HYDROLASE Ligands: QIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-08-14
Ligands: QIN
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Crystal Structure Of Human Beta Secretase Complexed With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2007-08-14 Classification: HYDROLASE Ligands: MY9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-08-14
Ligands: MY9
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Crystal Structue Of Thrombin In Complex With A Potent P1 Heterocycle-Aryl Based Inhibitor
Organism: Homo sapiens, Hirudo medicinalis
Method: X-RAY DIFFRACTION Resolution:1.81 Å Release Date: 2004-08-03 Classification: BLOOD CLOTTING,HYDROLASE/INHIBITOR Ligands: 170 |
Organism: Homo sapiens, Hirudo medicinalis
Method: X-RAY DIFFRACTION
Release Date: 2004-08-03
Ligands: 170
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Crystal Structure Of Thrombin In Complex With L-378,622
Organism: Hirudo medicinalis, Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.99 Å Release Date: 2004-04-06 Classification: BLOOD CLOTTING,HYDROLASE/INHIBITOR Ligands: CDA |
Organism: Hirudo medicinalis, Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-04-06
Ligands: CDA
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Thrombin-Hirugen_L-378,650
Organism: Hirudo medicinalis, Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2004-04-06 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: CDB |
Organism: Hirudo medicinalis, Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-04-06
Ligands: CDB
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Thrombin In Complex With Selective Macrocyclic Inhibitor At 1.8A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2003-09-02 Classification: BLOOD CLOTTING/HYDROLASE INHIBITOR Ligands: L86 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2003-09-02
Ligands: L86