Search Count: 31
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Discovery Of An Orally Bioavailable Reversible Covalent Sars-Cov-2 Mpro Inhibitor With Pan-Coronavirus Activity
Organism: Severe acute respiratory syndrome coronavirus 2, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.37 Å Release Date: 2025-08-20 Classification: HYDROLASE/INHIBOTOR Ligands: A1L7M |
Organism: Severe acute respiratory syndrome coronavirus 2, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2025-08-20
Ligands: A1L7M
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Discovery Of An Orally Bioavailable Reversible Covalent Sars-Cov-2 Mpro Inhibitor With Pan-Coronavirus Activity
Organism: Severe acute respiratory syndrome coronavirus 2, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2025-08-20 Classification: HYDROLASE/INHIBITOR |
Organism: Severe acute respiratory syndrome coronavirus 2, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2025-08-20
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Discovery Of An Orally Bioavailable Reversible Covalent Sars-Cov-2 Mpro Inhibitor With Pan-Coronavirus Activity
Organism: Severe acute respiratory syndrome coronavirus 2, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2025-08-20 Classification: HYDROLASE/INHIBITOR |
Organism: Severe acute respiratory syndrome coronavirus 2, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2025-08-20
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Discovery Of An Orally Bioavailable Reversible Covalent Sars-Cov-2 Mpro Inhibitor With Pan-Coronavirus Activity
Organism: Severe acute respiratory syndrome coronavirus 2, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.47 Å Release Date: 2025-08-20 Classification: HYDROLASE/INHIBITOR Ligands: A1L7M |
Organism: Severe acute respiratory syndrome coronavirus 2, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2025-08-20
Ligands: A1L7M
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Discovery Of An Orally Bioavailable Reversible Covalent Sars-Cov-2 Mpro Inhibitor With Pan-Coronavirus Activity
Organism: Severe acute respiratory syndrome coronavirus 2, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2025-08-20 Classification: HYDROLASE/INHIBITOR Ligands: A1L7M |
Organism: Severe acute respiratory syndrome coronavirus 2, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2025-08-20
Ligands: A1L7M
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Structure-Based Discovery Of Novel Non-Covalent Small Molecule Inhibitors Of Usp30
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.58 Å Release Date: 2025-05-21 Classification: HYDROLASE Ligands: A1L7W, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-21
Ligands: A1L7W, ZN
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Identification Of Small-Molecule Binding Sites Of A Ubiquitin-Conjugating Enzyme-Ube2T Through Fragment-Based Screening
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.54 Å Release Date: 2024-02-28 Classification: LIGASE Ligands: V23, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-02-28
Ligands: V23, EDO
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Identification Of Small-Molecule Binding Sites Of A Ubiquitin-Conjugating Enzyme-Ube2T Through Fragment-Based Screening
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2024-02-28 Classification: LIGASE Ligands: V2R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-02-28
Ligands: V2R
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Identification And Characterization Of Inhibitors Covalently Modifying Catalytic Cysteine Of Ube2T And Blocking Ubiquitin Transfer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2023-11-29 Classification: LIGASE/INHIBITOR Ligands: V6C, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-11-29
Ligands: V6C, EDO
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Identification And Characterization Of Inhibitors Covalently Modifying Catalytic Cysteine Of Ube2T And Blocking Ubiquitin Transfer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2023-11-29 Classification: LIGASE/INHIBITOR Ligands: V5L, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-11-29
Ligands: V5L, EDO
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Structure-Activity Relationship Studies Of Allosteric Inhibitors Of Eya2 Tyrosine Phosphatase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.49 Å Release Date: 2021-12-29 Classification: TRANSCRIPTION Ligands: 1RI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-12-29
Ligands: 1RI
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Structure-Activity Relationship Studies Of Allosteric Inhibitors Of Eya2 Tyrosine Phosphatase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.30 Å Release Date: 2021-12-29 Classification: TRANSCRIPTION Ligands: 1SI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-12-29
Ligands: 1SI
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Fragment-Based Lead Discovery Of Indazole-Based Compounds As Axl Kinase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.15 Å Release Date: 2021-10-13 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: E56 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-10-13
Ligands: E56
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Strategic Design Of Catalytic Lysine-Targeting Reversible Covalent Bcr-Abl Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.72 Å Release Date: 2021-06-09 Classification: TRANSFERASE Ligands: FVC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-06-09
Ligands: FVC
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Strategic Design Of Catalytic Lysine-Targeting Reversible Covalent Bcr-Abl Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2021-06-09 Classification: TRANSFERASE Ligands: HJ9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-06-09
Ligands: HJ9
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Structure Of Human Pycr2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.40 Å Release Date: 2020-10-28 Classification: OXIDOREDUCTASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-10-28
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Crystal Structure Of Wild Type Mnk2 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2020-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: BV9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-02-12
Ligands: BV9
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Crystal Structure Of Smyd3 In Complex With Covalent Inhibitor 5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2019-08-14 Classification: TRANSFERASE/INHIBITOR Ligands: A8U, ZN, SAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-08-14
Ligands: A8U, ZN, SAM
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Crystal Structure Of Pkciota In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.26 Å Release Date: 2019-06-26 Classification: TRANSFERASE Ligands: AFU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-06-26
Ligands: AFU
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Structural Basis For An Allosteric Eya2 Phosphatase Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.18 Å Release Date: 2019-06-05 Classification: TRANSCRIPTION Ligands: 9FX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-06-05
Ligands: 9FX