Search Count: 20
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Discovery Of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate In Vivo Activity In Mouse Xenograft Models Of Human Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2019-04-17 Classification: APOPTOSIS Ligands: KJP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-17
Ligands: KJP
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Ras:Sos:Ras In Complex With A Small Molecule Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2019-03-27 Classification: SIGNALING PROTEIN Ligands: MG, GNP, FVV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-27
Ligands: MG, GNP, FVV
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Ras:Sos:Ras In Complex With A Small Molecule Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: GNP, MG, FWA, FMT, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: GNP, MG, FWA, FMT, GOL, NA
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Ras:Sos:Ras In Complex With A Small Molecule Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: GNP, MG, FVM, FMT, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: GNP, MG, FVM, FMT, GOL, NA
 |
Ras:Sos:Ras In Complex With A Small Molecule Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: GNP, MG, FVJ, FMT, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: GNP, MG, FVJ, FMT, GOL, NA
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Ras:Sos:Ras In Complex With A Small Molecule Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: GNP, MG, CL, FVG, FMT, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: GNP, MG, CL, FVG, FMT, GOL, NA
 |
Ras:Sos:Ras In Complex With A Small Molecule Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: GNP, MG, FMT, CL, FVD, GOL, BME |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: GNP, MG, FMT, CL, FVD, GOL, BME
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Ras:Sos:Ras In Complex With A Small Molecule Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: GNP, MG, CL, FV7, FMT, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: GNP, MG, CL, FV7, FMT, GOL
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Ras:Sos:Ras In Complex With A Small Molecule Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: GNP, MG, FV4, FMT, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: GNP, MG, FV4, FMT, GOL, NA
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Ras:Sos:Ras In Complex With A Small Molecule Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: GNP, MG, FMT, FW7, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: GNP, MG, FMT, FW7, GOL, NA
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Ras:Sos:Ras In Complex With A Small Molecule Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: MG, GNP, FW4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: MG, GNP, FW4
 |
Ras:Sos:Ras In Complex With A Small Molecule Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2018-09-19 Classification: SIGNALING PROTEIN Ligands: MG, GNP, FVY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: MG, GNP, FVY
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Understanding The Species Selectivity Of Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors
Organism: Escherichia coli (strain k12), Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2018-08-01 Classification: SIGNALING PROTEIN/INHIBITOR Ligands: 6AK |
Organism: Escherichia coli (strain k12), Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2018-08-01
Ligands: 6AK
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Mcl-1 Complexed With Small Molecules
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2018-01-31 Classification: APOPTOSIS Ligands: ECY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-31
Ligands: ECY
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Mcl-1 Complexed With Small Molecules
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2018-01-31 Classification: APOPTOSIS Ligands: ECM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-31
Ligands: ECM
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Discovery Of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors Using Structure-Based Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2017-01-18 Classification: apoptosis/apoptosis inhibitor Ligands: 6AL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-01-18
Ligands: 6AL
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Discovery Of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors Using Structure-Based Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2017-01-18 Classification: apoptosis/apoptosis inhibitor Ligands: 6AK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-01-18
Ligands: 6AK
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Mcl-1 Complexed With Small Molecule Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2016-03-02 Classification: apoptosis/apoptosis inhibitor Ligands: 5WL, 5WK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-02
Ligands: 5WL, 5WK
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Mcl-1 Complexed With Small Molecule Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2016-03-02 Classification: apoptosis/apoptosis inhibitor Ligands: 5X2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-02
Ligands: 5X2
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Mcl-1 Complexed With Small Molecule Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2016-03-02 Classification: APOPTOSIS/APOPTOSIS inhibitor Ligands: 5X3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-02
Ligands: 5X3