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Discovery Of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(Trifluoromethoxy)Phenyl]-2-Methoxyethyl}-7-Methoxy-2-Oxo-2,3-Dihydropyrido[2,3-B]Pyrazine-4(1H)-Carboxamide (Tak-915), A Highly Potent, Selective, And Brain-Penetrating Phosphodiesterase 2A Inhibitor For The Treatment Of Cognitive Disorders
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