ISDA: 9ZZR

Deposition Date 2026-01-07

Release Date 2026-04-01

Last Version Date 2026-04-01

Entry Detail

PDB ID:

9ZZR

Keywords:

DNA BINDING PROTEIN/DNA

Title:

Cryo-EM Structure of a RAD51 filament bound by ssDNA and the XRCC3-RAD51C-RAD51D-XRCC2 paralog complex

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli, Trichoplusia ni

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.95 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA repair protein XRCC3
Gene (Uniprot):XRCC3
Chain IDs:K (auth: B)
Chain Length:346
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O43542 Pfam ID:PF26169, PF08423

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA repair protein RAD51 homo
Gene (Uniprot):RAD51C
Chain IDs:J (auth: C)
Chain Length:339
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O43502 Pfam ID:PF08423

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA repair protein RAD51 homo
Gene (Uniprot):RAD51D
Chain IDs:I (auth: D)
Chain Length:313
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O75771 Pfam ID:PF21794, PF08423

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA repair protein RAD51 homo
Gene (Uniprot):RAD51
Chain IDs:L (auth: F)
Chain Length:314
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q06609 Pfam ID:PF14520, PF08423 EC:3.6.4.B7

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*TP*TP*TP*TP*TP*TP
Chain IDs:G (auth: J)
Chain Length:23
Number of Molecules:1
Biological Source:synthetic construct

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA repair protein RAD51 homo
Gene (Uniprot):RAD51
Chain IDs:A (auth: R), B (auth: V)
Chain Length:316
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q06609 Pfam ID:PF14520, PF08423 EC:3.6.4.B7

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA repair protein RAD51 homo
Gene (Uniprot):RAD51
Chain IDs:C (auth: W), D (auth: O), E, F (auth: K)
Chain Length:317
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:Q06609 Pfam ID:PF14520, PF08423 EC:3.6.4.B7

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA repair protein XRCC2
Gene (Uniprot):XRCC2
Chain IDs:H (auth: X)
Chain Length:260
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O43543 Pfam ID:PF08423

Ligand Molecules

ANP

Primary Citation

Cryo-EM Structure of a RAD51 filament bound by ssDNA and the XRCC3-RAD51C-RAD51D-XRCC2 paralog complex

Ruben, E.A, Jia, L, Olsen, S.K, Wasmuth, E.V, Rawal, Y, Kwon, Y, Sung, P.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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