ISDA: 9ZEN

Deposition Date 2025-11-30

Release Date 2026-03-04

Last Version Date 2026-03-04

Entry Detail

PDB ID:

9ZEN

Keywords:

DE NOVO PROTEIN

Title:

Competition for different elements of the nucleosome acidic patch yields distinct functional outcomes. VHH 1B2

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
artificial sequences (Taxon ID: 81077)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.17 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H3.2
Gene (Uniprot):H3C15, H3C14, H3C13
Mutagens:C97S
Chain IDs:A, E
Chain Length:97
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q71DI3 Pfam ID:PF00125

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H4
Gene (Uniprot):H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16
Chain IDs:B, F
Chain Length:79
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P62805 Pfam ID:PF15511

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H2A type 1-B/E
Gene (Uniprot):H2AC4, H2AC8
Chain IDs:C, G
Chain Length:111
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P04908 Pfam ID:PF00125, PF16211

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H2B type 1-K
Gene (Uniprot):H2BC12
Chain IDs:D, H
Chain Length:93
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:O60814 Pfam ID:PF00125

Polymer Type:polydeoxyribonucleotide
Molecule:DNA Tracking Strand
Chain IDs:I
Chain Length:145
Number of Molecules:1
Biological Source:artificial sequences

Polymer Type:polydeoxyribonucleotide
Molecule:DNA lagging strand
Chain IDs:J
Chain Length:145
Number of Molecules:1
Biological Source:artificial sequences

Polymer Type:polypeptide(L)
Molecule:Single-chain antibody (VHH) 1
Chain IDs:K (auth: L), L (auth: K)
Chain Length:119
Number of Molecules:2
Biological Source:artificial sequences

Ligand Molecules

Primary Citation

Competition for different elements of the nucleosome acidic patch yields distinct functional outcomes

Chakraborty, U, Saccone, E.C, Becerra, G.C, Khan, L.F, Arslanovic, N, Aguilar, R, Gloor, S.L, Hunt, S.R, Folkwein, H.J, Husby, N.L, Maier, K.E, Marunde, M.R, Schomburg, N.K, Vaidya, A, Cowles, M.W, Venters, B.J, Kassavetis, G, Sun, Z.-W, Kadonaga, J.T, Armache, J.-P, Keogh, M.-C, Tyler, J.K.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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