9ZCW image
Deposition Date 2025-11-24
Release Date 2026-04-01
Last Version Date 2026-04-01
Entry Detail
PDB ID:
9ZCW
Keywords:
VIRUS
Title:
Cryo-EM structure of the engineered vector AAV2.ATX002
Biological Source:
Source Organism(s):
adeno-associated virus 2 (Taxon ID: 10804)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
1.90 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9ZCW validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Engineered AAV2 capsid protei
Gene (Uniprot):VP1
Chain IDs:A (auth: 1), B (auth: 2), C (auth: 3), D (auth: 4), E (auth: 5), F (auth: 6), G (auth: 7), H (auth: 8), I (auth: A), J (auth: B), K (auth: C), L (auth: D), M (auth: E), N (auth: F), O (auth: G), P (auth: H), Q (auth: I), R (auth: J), S (auth: K), T (auth: L), U (auth: M), V (auth: N), W (auth: O), X (auth: P), Y (auth: Q), Z (auth: R), AA (auth: S), BA (auth: T), CA (auth: U), DA (auth: V), EA (auth: W), FA (auth: X), GA (auth: Y), HA (auth: Z), IA (auth: a), JA (auth: b), KA (auth: c), LA (auth: d), MA (auth: e), NA (auth: f), OA (auth: g), PA (auth: h), QA (auth: i), RA (auth: j), SA (auth: k), TA (auth: l), UA (auth: m), VA (auth: n), WA (auth: o), XA (auth: p), YA (auth: q), ZA (auth: r), AB (auth: s), BB (auth: t), CB (auth: u), DB (auth: v), EB (auth: w), FB (auth: x), GB (auth: y), HB (auth: z)
Chain Length:542
Number of Molecules:60
Biological Source:adeno-associated virus 2
UniProt ID:P03135 Pfam ID:PF00740 EC:3.1.1.4
Ligand Molecules
NA
Primary Citation
Structural dynamics insights into principles underlying the increased fitness of newly engineered and broadly potent AAV capsids
To Be Published ? ? ? (?)
Primary Citation of related structures
9ZCW
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