9ZCV image
Deposition Date 2025-11-24
Release Date 2026-03-25
Last Version Date 2026-04-08
Entry Detail
PDB ID:
9ZCV
Keywords:
MEMBRANE PROTEIN
Title:
Human TRPM8 fully-swapped, desensitized, ligand-free structure at 4 degrees Celsius resolved in cell vesicles
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.65 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9ZCV validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transient receptor potential
Gene (Uniprot):TRPM8
Chain IDs:A (auth: B), B (auth: C), C (auth: D), D (auth: A)
Chain Length:1111
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:Q7Z2W7 Pfam ID:PF18139, PF25508, PF00520
Ligand Molecules
NA
Primary Citation
Structural energetics of cold sensitivity.
Nature ? ? ? (2026)
PMID: 41882351 DOI: 10.1038/s41586-026-10276-2
Primary Citation of related structures
9ZCV
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