9Z30 image
Deposition Date 2025-11-05
Release Date 2026-04-08
Last Version Date 2026-04-08
Entry Detail
PDB ID:
9Z30
Title:
Solution NMR Structure of the PACS1 Furin binding region (FBR)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Conformers Calculated:
1000
Conformers Submitted:
40
Selection Criteria:
structures with the lowest energy
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Phosphofurin acidic cluster s
Chain IDs:A
Chain Length:173
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
Primary Citation
The R203W substitution drives PACS-1 syndrome by disrupting intramolecular regulation.
Febs J. ? ? ? (2026)
PMID: 41858172 DOI: 10.1111/febs.70492
Primary Citation of related structures
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