ISDA: 9Z1Q

Deposition Date 2025-11-04

Release Date 2026-03-18

Last Version Date 2026-03-25

Entry Detail

PDB ID:

9Z1Q

Keywords:

TRANSCRIPTION

Title:

Backbone Modification in the GCN4 Leucine Zipper: Calpha-methyl-Glu at position 11

Biological Source:

Source Organism(s):

Saccharomyces cerevisiae (Taxon ID: 4932)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.80 Å

R-Value Free:

0.19

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:General control transcription
Gene (Uniprot):GCN4
Chain IDs:A, B
Chain Length:35
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae

UniProt ID:P03069 Pfam ID:PF07716

Modified Residue

Compound ID	Chain ID	Parent Comp ID	Details	2D Image
GAM	A	GLU	modified residue

Primary Citation

Manipulating the Unfolded State of a Folded Protein through Site-Specific Backbone Modification.

Page, G.E, Lin, Y, Horne, W.S, Liebschner, D, Afonine, P.V, Baker, M.L, Bunkoczi, G, Chen, V.B, Croll, T.I, Hintze, B, Hung, L.W, Jain, S, McCoy, A.J, Moriarty, N.W, Oeffner, R.D, Poon, B.K, Prisant, M.G, Read, R.J, Richardson, J.S, Richardson, D.C, Sammito, M.D, Sobolev, O.V, Stockwell, D.H, Terwilliger, T.C, Urzhumtsev, A.G, Videau, L.L, Williams, C.J, Adams, P.D.Show

Biochemistry 65 693 703 (2026)

PMID: 41773780 DOI: 10.1021/acs.biochem.5c00687

Primary Citation of related structures

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