ISDA: 9YXD

Deposition Date 2025-10-27

Release Date 2026-03-11

Last Version Date 2026-03-11

Entry Detail

PDB ID:

9YXD

Keywords:

HORMONE

Title:

Crystal structure of recombinant human follicle stimulating hormone in complex with an anti-FSH alpha Fab

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Mus musculus (Taxon ID: 10090)
Lama glama (Taxon ID: 9844)

Expression System(s):

Homo sapiens, Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.29 Å

R-Value Free:

0.23

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Glycoprotein hormones alpha c
Gene (Uniprot):CGA
Chain IDs:A
Chain Length:92
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P01215 Pfam ID:PF00236

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Follitropin subunit beta
Gene (Uniprot):FSHB
Chain IDs:B
Chain Length:111
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P01225 Pfam ID:PF00007

Polymer Type:polypeptide(L)
Molecule:Fab light chain
Chain IDs:C
Chain Length:220
Number of Molecules:1
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:Fab heavy chain
Chain IDs:D
Chain Length:225
Number of Molecules:1
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:Ig-like domain-containing pro
Chain IDs:E (auth: K)
Chain Length:127
Number of Molecules:1
Biological Source:Lama glama

Ligand Molecules