9XRO image
Deposition Date 2025-11-19
Release Date 2026-03-18
Last Version Date 2026-04-01
Entry Detail
PDB ID:
9XRO
Keywords:
TRANSPORT PROTEIN
Title:
LolCDE in complex with SMT-738_3
Biological Source:
Source Organism(s):
Escherichia coli K-12 (Taxon ID: 83333)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.88 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9XRO validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Lipoprotein-releasing system
Gene (Uniprot):lolC
Chain IDs:A (auth: C)
Chain Length:399
Number of Molecules:1
Biological Source:Escherichia coli K-12
UniProt ID:P0ADC3 Pfam ID:PF12704, PF02687
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Lipoprotein-releasing system
Gene (Uniprot):lolE
Chain IDs:B (auth: E)
Chain Length:414
Number of Molecules:1
Biological Source:Escherichia coli K-12
UniProt ID:P75958 Pfam ID:PF12704, PF02687
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Lipoprotein-releasing system
Gene (Uniprot):lolD
Chain IDs:C (auth: F)
Chain Length:241
Number of Molecules:1
Biological Source:Escherichia coli K-12
UniProt ID:P75957 Pfam ID:PF00005
Ligand Molecules
A1ER4
Primary Citation
Molecular mechanism of action of small molecule SMT-738 on bacterial lipoprotein transporter LolCDE.
Nat Commun 17 ? ? (2026)
PMID: 41663437 DOI: 10.1038/s41467-026-69411-2
Primary Citation of related structures
9XRO
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