ISDA: 9X86

Deposition Date 2025-10-18

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9X86

Keywords:

LYASE

Title:

Crystal Structure of dehydratase ApmL in Amipurimycin biosynthesis

Biological Source:

Source Organism(s):

Streptomyces novoguineensis (Taxon ID: 2586640)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.50 Å

R-Value Free:

0.32

R-Value Work:

0.26

R-Value Observed:

0.26

Space Group:

P 61 2 2

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Amc20
Chain IDs:A
Chain Length:297
Number of Molecules:1
Biological Source:Streptomyces novoguineensis

Primary Citation

Deoxysugar Formation via 4',5'-Dehydration on PKS Assembly Line in Nucleoside Antibiotic Biosynthesis.

Chen, Z.H, Wang, F, Wang, W, Zhang, T.C, Wang, Y.L, Zhang, W.H, Pu, J, Sun, A, Pan, H.X, Tang, G.L.Show

Angew.Chem.Int.Ed.Engl. ? e6927983 e6927983 (2026)

PMID: 41902592 DOI: 10.1002/anie.6927983

Primary Citation of related structures

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