ISDA: 9WQY

Deposition Date 2025-09-11

Release Date 2026-04-01

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9WQY

Keywords:

TRANSFERASE

Title:

aminoacyl-tRNA-dependent peptide synthase, Sba18, complexed with streptothrisamine

Biological Source:

Source Organism(s):

Streptomyces sp. (Taxon ID: 1931)

Expression System(s):

Escherichia coli m15

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.00 Å

R-Value Free:

0.23

R-Value Work:

0.18

R-Value Observed:

0.19

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:aminoacyl-tRNA-dependent pept
Chain IDs:A
Chain Length:312
Number of Molecules:1
Biological Source:Streptomyces sp.

Ligand Molecules

A1L3W

TRS

Primary Citation

tRNA-Dependent Chemoenzymatic Transformation of Aminoacyl Pendant Moieties of Streptothricin Antibiotics.

Maruyama, C, Nakashima, Y, Matsuda, K, A Hamdy, S, Uchiyama, S, Goto, Y, Mori, T, Ogasawara, Y, Shin-Ya, K, Abe, I, Dairi, T, Suga, H, Morita, H, Hamano, Y.Show

J.Am.Chem.Soc. 148 12154 12165 (2026)

PMID: 41823201 DOI: 10.1021/jacs.6c00367

Primary Citation of related structures

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