9WDB image
Deposition Date 2025-08-18
Release Date 2026-04-01
Last Version Date 2026-04-01
Entry Detail
PDB ID:
9WDB
Keywords:
STRUCTURAL PROTEIN
Title:
Paclitaxel/GMPCPP-stabilized human alpha1A/beta3 S239C microtubule
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Trichoplusia ni
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.39 Å
Aggregation State:
HELICAL ARRAY
Reconstruction Method:
SINGLE PARTICLE
9WDB validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Tubulin alpha-1A chain
Gene (Uniprot):TUBA1A
Chain IDs:A (auth: a)
Chain Length:451
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q71U36 Pfam ID:PF00091, PF03953
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Tubulin beta-3 chain
Gene (Uniprot):TUBB3
Mutagens:S239c
Chain IDs:B (auth: b)
Chain Length:450
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q13509 Pfam ID:PF00091, PF03953
Ligand Molecules
G2P
GTP
MG
TA1
Primary Citation
Allosteric modulation of paclitaxel efficacy by human tubulin variants
To Be Published ? ? ? (?)
Primary Citation of related structures
9WDB
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