9W2U image
Deposition Date 2025-07-28
Release Date 2026-04-01
Last Version Date 2026-04-01
Entry Detail
PDB ID:
9W2U
Keywords:
OXIDOREDUCTASE
Title:
Cryo-EM structure of complex I on the bovine heart submitochondrial particles, open
Biological Source:
Source Organism(s):
Bos taurus (Taxon ID: 9913)
Expression System(s):
Bos taurus
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.60 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9W2U validation report
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:B (auth: A)
Chain Length:70
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:C (auth: B)
Chain Length:83
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:D (auth: C)
Chain Length:209
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:E (auth: D)
Chain Length:119
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:F (auth: E)
Chain Length:214
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:G (auth: F)
Chain Length:432
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:H (auth: G)
Chain Length:699
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:I (auth: H)
Chain Length:317
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:J (auth: I)
Chain Length:176
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:A (auth: J)
Chain Length:71
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:K
Chain Length:81
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:L
Chain Length:605
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:M
Chain Length:458
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:N
Chain Length:172
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:O
Chain Length:320
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:P
Chain Length:173
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:Q
Chain Length:129
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:R
Chain Length:96
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:S
Chain Length:87
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:Acyl carrier protein, mitocho
Chain IDs:T
Chain Length:141
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:Acyl carrier protein, mitocho
Chain IDs:U
Chain Length:86
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:V
Chain Length:115
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:W
Chain Length:115
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:X
Chain Length:171
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:Z
Chain Length:141
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:AA (auth: a)
Chain Length:70
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:BA (auth: b)
Chain Length:83
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:CA (auth: c)
Chain Length:209
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:DA (auth: d)
Chain Length:119
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:EA (auth: e)
Chain Length:214
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:FA (auth: f)
Chain Length:432
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:GA (auth: g)
Chain Length:699
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:HA (auth: h)
Chain Length:317
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:JA (auth: j)
Chain Length:71
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:KA (auth: k)
Chain Length:81
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:LA (auth: l)
Chain Length:605
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:MA (auth: m)
Chain Length:458
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:NA (auth: n)
Chain Length:172
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:OA (auth: o)
Chain Length:320
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:PA (auth: p)
Chain Length:173
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:QA (auth: q)
Chain Length:129
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:SA (auth: s)
Chain Length:87
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:Y (auth: t)
Chain Length:141
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:IA (auth: u)
Chain Length:86
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:RA (auth: v)
Chain Length:115
Number of Molecules:1
Biological Source:Bos taurus
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
2MR E ARG modified residue
FME A MET modified residue
Ligand Molecules
3PE
CDL
CHD
FES
FME
FMN
GTP
K
MG
MYR
NDP
PC1
SF4
ZN
Primary Citation
Structures of respiratory supercomplexes and ATP synthase oligomers in mammalian mitochondrial inner membrane.
Nat Commun ? ? ? (2026)
PMID: 41844608 DOI: 10.1038/s41467-026-70578-x
Primary Citation of related structures
9W2U
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