ISDA: 9VNF

Deposition Date 2025-06-30

Release Date 2025-11-12

Last Version Date 2026-04-01

Entry Detail

PDB ID:

9VNF

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of 5-HT1AR-GoA in complex with (S)-pindolol

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Mus musculus (Taxon ID: 10090)
Escherichia coli (Taxon ID: 562)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.74 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAO1
Chain IDs:A (auth: B)
Chain Length:354
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P09471 Pfam ID:PF00503

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:B (auth: C)
Chain Length:358
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62873 Pfam ID:PF00400, PF25391

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C (auth: D)
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P59768 Pfam ID:PF00631

Polymer Type:polypeptide(L)
Molecule:scFv16
Chain IDs:D (auth: E)
Chain Length:251
Number of Molecules:1
Biological Source:Mus musculus

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Soluble cytochrome b562,5-hyd
Gene (Uniprot):HTR1A, cybC
Chain IDs:E (auth: R)
Chain Length:549
Number of Molecules:1
Biological Source:Escherichia coli, Homo sapiens

UniProt ID:P0ABE7,P08908 Pfam ID:PF07361, PF00001

Ligand Molecules