9VEF image
Deposition Date 2025-06-09
Release Date 2026-04-08
Last Version Date 2026-04-08
Entry Detail
PDB ID:
9VEF
Keywords:
MEMBRANE PROTEIN
Title:
The cryo-EM structure of human Piezo2-MDFIC complex (composite map)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Aequorea victoria (Taxon ID: 6100)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.75 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9VEF validation report
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Piezo-type mechanosensitive i
Chain IDs:A, C, E
Chain Length:3020
Number of Molecules:3
Biological Source:Homo sapiens, Aequorea victoria
Polymer Type:polypeptide(L)
Molecule:MyoD family inhibitor domain-
Chain IDs:B, D, F
Chain Length:267
Number of Molecules:3
Biological Source:Homo sapiens
Ligand Molecules
NA
Primary Citation
MDFIC2 is a sensory neuron-specific PIEZO channel auxiliary subunit
Proc.Natl.Acad.Sci.USA ? ? ? (2026)
Primary Citation of related structures
9VEF
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