9VDZ image
Deposition Date 2025-06-09
Release Date 2026-01-07
Last Version Date 2026-02-25
Entry Detail
PDB ID:
9VDZ
Keywords:
VIRAL PROTEIN/IMMUNE SYSTEM
Title:
hA5-6(W30B/E45) Fab bound to SFTSV glycoprotein Gn
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Severe fever with thrombocytopenia syndrome virus (Taxon ID: 1003835)
Expression System(s):
Homo sapiens, Trichoplusia ni
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.43 Å
R-Value Free:
0.25
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
P 2 21 21
9VDZ validation report
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:hA5-6(W30B/E45) Fab heavy cha
Chain IDs:A, E (auth: H)
Chain Length:232
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:hA5-6(W30B/E45) Fab light cha
Chain IDs:B, F (auth: L)
Chain Length:218
Number of Molecules:2
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Envelopment polyprotein
Chain IDs:C, D
Chain Length:338
Number of Molecules:2
Biological Source:Severe fever with thrombocytopenia syndrome virus
UniProt ID:W5VWE0 Pfam ID:PF07243
Primary Citation
Humanization and engineering of protective antibodies targeting severe fever with thrombocytopenia syndrome virus Gn protein.
Cell Rep 45 116936 116936 (2026)
PMID: 41671090 DOI: 10.1016/j.celrep.2026.116936
Primary Citation of related structures
9VDZ
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