ISDA: 9V33

Deposition Date 2025-05-21

Release Date 2026-03-18

Last Version Date 2026-03-18

Entry Detail

PDB ID:

9V33

Keywords:

TRANSCRIPTION/DNA

Title:

Calypso/Asx/NCP-ub complex

Biological Source:

Source Organism(s):

Xenopus laevis (Taxon ID: 8355)
Drosophila melanogaster (Taxon ID: 7227)
Homo sapiens (Taxon ID: 9606)
Escherichia coli (Taxon ID: 562)

Expression System(s):

Escherichia coli, Trichoplusia ni

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

5.90 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H3
Gene (Uniprot):LOC121398065
Chain IDs:A, E
Chain Length:136
Number of Molecules:2
Biological Source:Xenopus laevis

UniProt ID:A0A310TTQ1 Pfam ID:PF00125

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H4
Chain IDs:B, F
Chain Length:103
Number of Molecules:2
Biological Source:Xenopus laevis

UniProt ID:P62799 Pfam ID:PF15511

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H2A
Gene (Uniprot):LOC494591
Chain IDs:C, G
Chain Length:132
Number of Molecules:2
Biological Source:Xenopus laevis

UniProt ID:Q6AZJ8 Pfam ID:PF00125, PF16211

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H2B
Gene (Uniprot):LOC108704303
Chain IDs:D, H
Chain Length:123
Number of Molecules:2
Biological Source:Xenopus laevis

UniProt ID:A0A8J0U496 Pfam ID:PF00125

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (147-MER)
Chain IDs:I
Chain Length:147
Number of Molecules:1
Biological Source:Escherichia coli

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (147-MER)
Chain IDs:J
Chain Length:147
Number of Molecules:1
Biological Source:Escherichia coli

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ubiquitin carboxyl-terminal h
Gene (Uniprot):caly
Chain IDs:K, N
Chain Length:512
Number of Molecules:2
Biological Source:Drosophila melanogaster

UniProt ID:Q7K5N4 Pfam ID:PF01088, PF18031

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Polycomb group protein Asx
Gene (Uniprot):Asx
Chain IDs:L, O
Chain Length:340
Number of Molecules:2
Biological Source:Drosophila melanogaster

UniProt ID:Q9V727 Pfam ID:PF13919

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Polyubiquitin-B
Gene (Uniprot):UBB
Chain IDs:M
Chain Length:88
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P0CG47 Pfam ID:PF00240

Ligand Molecules

Primary Citation

Structural basis of nucleosome deubiquitination by the bidentate Calypso/Asx complex.

Wang, C, Sun, F, Zhao, H, Zhang, N, Guan, J, Zhou, Y, Shuai, W, Zheng, H, He, J.Show

Iscience 29 114958 114958 (2026)

PMID: 41782825 DOI: 10.1016/j.isci.2026.114958

Primary Citation of related structures

Feedback Form