9V0P image
Deposition Date 2025-05-18
Release Date 2025-12-31
Last Version Date 2026-03-04
Entry Detail
PDB ID:
9V0P
Keywords:
VIRAL PROTEIN
Title:
Cryo-EM structure of RSV pre-F in complex with antibody CNR2053
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Respiratory syncytial virus A2 (Taxon ID: 1972429)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.87 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9V0P validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:RSV Pre-fusion Protein
Chain IDs:C (auth: A), F (auth: B), I (auth: C)
Chain Length:553
Number of Molecules:3
Biological Source:Respiratory syncytial virus A2
UniProt ID:P03420
Polymer Type:polypeptide(L)
Molecule:CNR2053 Heavy Chain
Chain IDs:A (auth: H), D, G (auth: E)
Chain Length:124
Number of Molecules:3
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:CNR2053 Light Chain
Chain IDs:B (auth: L), E (auth: F), H (auth: G)
Chain Length:112
Number of Molecules:3
Biological Source:Homo sapiens
Ligand Molecules
NA
Primary Citation
Antibody cocktails based on the occupationally acquired immunity of pediatricians neutralize and confer protection against RSV and hMPV.
Sci Transl Med 18 eadz4170 eadz4170 (2026)
PMID: 41706868 DOI: 10.1126/scitranslmed.adz4170
Primary Citation of related structures
9V0P
Feedback Form
Name
Email
Institute
Feedback