9UZ1 image
Deposition Date 2025-05-16
Release Date 2026-04-08
Last Version Date 2026-04-08
Entry Detail
PDB ID:
9UZ1
Keywords:
Title:
Crystal structure of the indoleamine 2,3-dioxygenagse 2 (IDO2) H143Y mutant complexed with L-Trp
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.35 Å
R-Value Free:
0.23
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
P 31 2 1
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Maltose/maltodextrin-binding
Mutagens:H143Y
Chain IDs:A
Chain Length:782
Number of Molecules:1
Biological Source:Homo sapiens
Peptide-like Molecules
PRD_900001
Primary Citation
Human IDO2 exhibits unique binding affinities distinct to those of human IDO1.
Febs J. ? ? ? (2026)
PMID: 41804238 DOI: 10.1111/febs.70476
Primary Citation of related structures
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