ISDA: 9UT3

Deposition Date 2025-05-02

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9UT3

Keywords:

REPLICATION

Title:

The helicase module of the helicase-primase complex from HHV1 bound with ssDNA and amenamevir

Biological Source:

Source Organism(s):

Human alphaherpesvirus 1 (Taxon ID: 10298)
Saccharomyces cerevisiae S288C (Taxon ID: 559292)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.88 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication helicase
Gene (Uniprot):HELI
Chain IDs:A
Chain Length:934
Number of Molecules:1
Biological Source:Human alphaherpesvirus 1

UniProt ID:P10189 Pfam ID:PF02689

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ubiquitin-like protein SMT3,D
Gene (Uniprot):UL52, SMT3
Mutagens:R64T/R71E
Chain IDs:B
Chain Length:1195
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C, Human alphaherpesvirus 1

UniProt ID:Q12306,P10236 Pfam ID:PF00240, PF03121

Polymer Type:polydeoxyribonucleotide
Molecule:synthetic DNA
Chain IDs:C (auth: D)
Chain Length:7
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules

A1BXD

Primary Citation

The helicase-primase complex from HHV1 bound with ssDNA and amenamevir

Sato, K, Kise, Y, Hamada, K, Nureki, O, Sengoku, T.Show

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Primary Citation of related structures

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