ISDA: 9UED

Deposition Date 2025-04-08

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9UED

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of human TRPV3 in complex with sevoflurane determined in MSP2N2 nanodisc

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Komagataella pastoris

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.29 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Transient receptor potential
Gene (Uniprot):TRPV3
Chain IDs:A, B, C, D
Chain Length:802
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:Q8NET8 Pfam ID:PF12796, PF00023, PF00520

Ligand Molecules

A1IPI

POV

Primary Citation

Vagal nerve TRPV3 regulates sedative-mediated appeasement

Wang, P, Zhu, J, Lu, X, Chen, C, Gao, B, Xia, K, Pang, P, Li, Y, Mo, X, Xie, C, Li, D, Zhang, Z, Yao, J.Show

Proc.Natl.Acad.Sci.USA ? ? ? (2026)

Primary Citation of related structures

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