ISDA: 9UD7

Deposition Date 2025-04-06

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9UD7

Keywords:

TRANSFERASE

Title:

Crystal structure of human glutaminyl cyclase in complex with Inhibitor CL7

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.49 Å

R-Value Free:

0.22

R-Value Work:

0.15

R-Value Observed:

0.16

Space Group:

P 21 21 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Glutaminyl-peptide cyclotrans
Gene (Uniprot):QPCT
Chain IDs:A, B, C, D, E, F
Chain Length:361
Number of Molecules:6
Biological Source:Homo sapiens

UniProt ID:Q16769 Pfam ID:PF04389 EC:2.3.2.5

Ligand Molecules

A1EOY

GOL

TRS

Primary Citation

Crystal structure of human glutaminyl cyclase in complex with Inhibitor CL7

Li, G.-B, Ning, X.-L, Meng, F.-B, Chen, Y.-T.Show

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