ISDA: 9UC4

Deposition Date 2025-04-03

Release Date 2026-02-18

Last Version Date 2026-03-04

Entry Detail

PDB ID:

9UC4

Keywords:

MEMBRANE PROTEIN

Title:

Crystal structure of voltage-gated sodium channel NavAb N49K/S178T/T206A mutant

Biological Source:

Source Organism(s):

Aliarcobacter butzleri (Taxon ID: 28197)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.40 Å

R-Value Free:

0.31

R-Value Work:

0.27

R-Value Observed:

0.28

Space Group:

I 4 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ion transport protein
Gene (Uniprot):Abu_1752
Mutagens:N49K, S178T, T206A
Chain IDs:A
Chain Length:271
Number of Molecules:1
Biological Source:Aliarcobacter butzleri

UniProt ID:A8EVM5 Pfam ID:PF00520

Ligand Molecules

1N7

LMT

PX4

Primary Citation

Structure-function analysis of the lithium-ion selectivity of the voltage-gated sodium channel.

Maeda, Y.K, Kojima, K, Nakamura, T.Y, Nakatsu, T, Irie, K.Show

J.Gen.Physiol. 158 ? ? (2026)

PMID: 41711638 DOI: 10.1085/jgp.202513855

Primary Citation of related structures

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