ISDA: 9UAY

Deposition Date 2025-04-01

Release Date 2026-03-11

Last Version Date 2026-03-11

Entry Detail

PDB ID:

9UAY

Keywords:

TRANSFERASE

Title:

Crystal structure of CmnI

Biological Source:

Source Organism(s):

Saccharothrix mutabilis subsp. capreolus (Taxon ID: 66854)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.17 Å

R-Value Free:

0.24

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

C 1 2 1

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:CmnI
Chain IDs:A, B
Chain Length:568
Number of Molecules:2
Biological Source:Saccharothrix mutabilis subsp. capreolus

Ligand Molecules

AE3

AE4

PEG

PG4

Primary Citation

Biosynthesis of Antituberculosis Antibiotic Capreomycin Involves a trans -Iterative Adenylation Domain within the Nonribosomal Peptide Synthetase Machinery.

Lai, Y.T, Peng, C.Y, Liao, H.T, Hsiao, P.Y, Hsieh, C.K, Luo, Y.R, Huang, S.C, Wang, Y.L, Ma, T, Chen, Y.R, Kuo, Y.M, Lin, Y.C, Chu, J, Chang, C.Y.Show

Org.Lett. 27 9553 9558 (2025)

PMID: 40815678 DOI: 10.1021/acs.orglett.5c03112

Primary Citation of related structures

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