ISDA: 9UAF

Deposition Date 2025-03-31

Release Date 2026-03-11

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9UAF

Keywords:

OXIDOREDUCTASE

Title:

Crystal structure of the OkaE-M71A mutant with a-ketoglutarate

Biological Source:

Source Organism(s):

Penicillium simplicissimum (Taxon ID: 69488)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.54 Å

R-Value Free:

0.24

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Iron/alpha-ketoglutarate-depe
Chain IDs:A (auth: C), B (auth: D), C (auth: A), D (auth: B)
Chain Length:315
Number of Molecules:4
Biological Source:Penicillium simplicissimum

Ligand Molecules

AKG

GOL

Primary Citation

Structural and mechanistic insights into azetidine-associated alpha KG-NHFe enzyme OkaE with multifunctional catalysis.

Wang, X, Yu, J, Liu, T, Zhang, X, Ju, M, Xie, Z, Naowarojna, N, Ping, L, Dong, Y, Gong, B, Xie, Y, Nie, Y, Hsiang, T, Wu, R, Zhang, L, Liu, P, Zhu, G, Yan, W, Liu, X.Show

Nat Commun 17 ? ? (2026)

PMID: 41702921 DOI: 10.1038/s41467-026-69519-5

Primary Citation of related structures

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