ISDA: 9UAD

Deposition Date 2025-03-31

Release Date 2026-03-11

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9UAD

Keywords:

OXIDOREDUCTASE

Title:

Crystal structure of the OkaE-M64A mutant with a-ketoglutarate and okaramine A

Biological Source:

Source Organism(s):

Penicillium simplicissimum (Taxon ID: 69488)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.44 Å

R-Value Free:

0.23

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Iron/alpha-ketoglutarate-depe
Chain IDs:A, B, C, D
Chain Length:315
Number of Molecules:4
Biological Source:Penicillium simplicissimum

Ligand Molecules

A1EMZ

AKG

Primary Citation

Structural and mechanistic insights into azetidine-associated alpha KG-NHFe enzyme OkaE with multifunctional catalysis.

Wang, X, Yu, J, Liu, T, Zhang, X, Ju, M, Xie, Z, Naowarojna, N, Ping, L, Dong, Y, Gong, B, Xie, Y, Nie, Y, Hsiang, T, Wu, R, Zhang, L, Liu, P, Zhu, G, Yan, W, Liu, X.Show

Nat Commun 17 ? ? (2026)

PMID: 41702921 DOI: 10.1038/s41467-026-69519-5

Primary Citation of related structures

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