ISDA: 9U9S

Deposition Date 2025-03-29

Release Date 2026-03-04

Last Version Date 2026-03-18

Entry Detail

PDB ID:

9U9S

Keywords:

TRANSPORT PROTEIN

Title:

ARF1(Q71L) bound M4-CTD-docked AP-4 core

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

6.80 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:AP-4 complex subunit beta-1
Chain IDs:A (auth: B)
Chain Length:576
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:AP-4 complex subunit epsilon-
Chain IDs:B (auth: E)
Chain Length:612
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:ADP-ribosylation factor 1
Chain IDs:C (auth: H)
Chain Length:164
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:AP-4 complex subunit mu-1
Chain IDs:D (auth: M)
Chain Length:453
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:AP-4 complex subunit sigma-1
Chain IDs:E (auth: S)
Chain Length:144
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Structural basis for the dynamic conformations of AP-4 and its association with ARF1.

Wang, Y, Li, W, Qiu, Y, Wu, S, Hong, L, Zhao, Y, Feng, W.Show

Nat Commun 17 ? ? (2026)

PMID: 41565640 DOI: 10.1038/s41467-026-68679-8

Primary Citation of related structures

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