ISDA: 9U8S

Deposition Date 2025-03-26

Release Date 2026-04-01

Last Version Date 2026-04-01

Entry Detail

PDB ID:

9U8S

Keywords:

LYASE

Title:

Crystal structure of thiamine pyrophosphate (TPP)-dependent alpha-imino acid decarboxylase (AzcB and AzcC) from Streptomyces mobaraensis in complex with TPP and 5-azacytosine.

Biological Source:

Source Organism(s):

Streptomyces mobaraensis (Taxon ID: 35621)

Expression System(s):

Streptomyces lividans

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.46 Å

R-Value Free:

0.23

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 1 21 1

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Thiamine pyrophosphate enzyme
Chain IDs:A, B, C, D, E, F
Chain Length:168
Number of Molecules:6
Biological Source:Streptomyces mobaraensis

Polymer Type:polypeptide(L)
Molecule:Thiamine pyrophosphate enzyme
Chain IDs:G, H, I, J, K, L
Chain Length:194
Number of Molecules:6
Biological Source:Streptomyces mobaraensis

Ligand Molecules

5AZ

GOL

TPP

Primary Citation

Crystal structure of thiamine pyrophosphate (TPP)-dependent decarboxylase (AzcB and AzcC complexes) from Streptomyces mobaraensis in complex with TPP and 5-azacytosine.

Nakashima, Y, Morita, H.Show

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Primary Citation of related structures

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