ISDA: 9U02

Deposition Date 2026-01-26

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9U02

Keywords:

PROTEIN FIBRIL

Title:

Medin fibril generated from the heterotypic interaction of Abeta40 and Medin.

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.70 Å

Aggregation State:

FILAMENT

Reconstruction Method:

HELICAL

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Lactadherin
Chain IDs:A, B, C (auth: F), D (auth: G), E (auth: C), F (auth: H), G (auth: D), H (auth: I), I (auth: E), J
Chain Length:50
Number of Molecules:10
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Medin drives Abeta40 to adopt Abeta42-like fibril polymorphs in vitro

Pradhan, B, Kumar, S.T, Wagner, J, Gallardo, R, Zorzini, V, Orlando, G, Vleeschouwer, M.D, Madine, J, Louros, N, Neher, J, Schymkowitz, J, Rousseau, F.Show

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Primary Citation of related structures

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