ISDA: 9TM1

Deposition Date 2025-12-11

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9TM1

Keywords:

TRANSFERASE

Title:

Crystal structure of bromodomain from Plasmodium falciparum GCN5 complexed with a ligand

Biological Source:

Source Organism(s):

Plasmodium falciparum 3D7 (Taxon ID: 36329)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.80 Å

R-Value Free:

0.24

R-Value Work:

0.19

R-Value Observed:

0.20

Space Group:

P 21 21 2

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:histone acetyltransferase
Gene (Uniprot):PF3D7_0823300
Chain IDs:A, B, C
Chain Length:106
Number of Molecules:3
Biological Source:Plasmodium falciparum 3D7

UniProt ID:Q8IB67 EC:2.3.1.48

Ligand Molecules

A1JWP

Primary Citation

Residue-Level Determination of Small-Molecule-Protein Affinities by Hydrogen-Deuterium Exchange Mass Spectrometry.

Lin, D, Magalhaes, L.G, McMillan, J, Eadsforth, T.C, Stewart, G, Cartmill, K.R, Postis, V.L.G, Masson, G.R.Show

J.Am.Soc.Mass.Spectrom. ? ? ? (2026)

PMID: 41915381 DOI: 10.1021/jasms.6c00020

Primary Citation of related structures

Feedback Form