ISDA: 9TEB

Deposition Date 2025-11-25

Release Date 2026-03-18

Last Version Date 2026-04-01

Entry Detail

PDB ID:

9TEB

Keywords:

HYDROLASE

Title:

Crystal structure of Nocardia cyriacigeorgica, class A beta-lactamase, NCY-1 bound to Avibactam

Biological Source:

Source Organism(s):

Nocardia cyriacigeorgica (Taxon ID: 135487)

Expression System(s):

Escherichia coli bl21

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.30 Å

R-Value Free:

0.17

R-Value Work:

0.15

R-Value Observed:

0.15

Space Group:

P 32 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-lactamase
Gene (Uniprot):bla
Chain IDs:A
Chain Length:264
Number of Molecules:1
Biological Source:Nocardia cyriacigeorgica

UniProt ID:A0A5R8NCK8

Ligand Molecules

FLC

NXL

Primary Citation

NCY-1 beta-Lactamase Activity Correlates With Antimicrobial Susceptibility of a Clinical Strain of Nocardia cyriacigeorgica.

Couston, J, Le Marchand, A, Hodille, E, Genestet, C, Joannard, B, Feuillard, J, Benito, Y, Dumitrescu, O, Blaise, M, Couston, J, Le-Marchand, A, Hodille, E, Genestet, C, Joannard, B, Feuillard, J, Benito, Y, Dumitrescu, O, Blaise, M.Show

Microbiologyopen 15 e70267 e70267 (2026)

PMID: 41860015 DOI: 10.1002/mbo3.70267

Primary Citation of related structures

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