9SMH image
Deposition Date 2025-09-08
Release Date 2026-03-18
Last Version Date 2026-03-18
Entry Detail
PDB ID:
9SMH
Keywords:
ELECTRON TRANSPORT
Title:
Reduced bovine complex I in lipid nanodisc, NADH-active-DDM
Biological Source:
Source Organism(s):
Bos taurus (Taxon ID: 9913)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.61 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9SMH validation report
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:A
Chain Length:70
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:B
Chain Length:84
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:C
Chain Length:266
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:D
Chain Length:463
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:E
Chain Length:249
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:F
Chain Length:464
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:G
Chain Length:154
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:H
Chain Length:318
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:I
Chain Length:212
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:J
Chain Length:108
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:K
Chain Length:98
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:L
Chain Length:606
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:M
Chain Length:129
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH-ubiquinone oxidoreductas
Chain IDs:N
Chain Length:347
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:O
Chain Length:343
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:P
Chain Length:380
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:Q
Chain Length:145
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:R
Chain Length:124
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:S
Chain Length:99
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:Acyl carrier protein, mitocho
Chain IDs:T, U
Chain Length:156
Number of Molecules:2
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:V
Chain Length:116
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:W
Chain Length:128
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:X
Chain Length:172
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:Y
Chain Length:141
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:Z
Chain Length:144
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:AA (auth: a)
Chain Length:70
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:BA (auth: b)
Chain Length:84
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:CA (auth: c)
Chain Length:266
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:DA (auth: d)
Chain Length:463
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:EA (auth: e)
Chain Length:249
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:FA (auth: f)
Chain Length:464
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:GA (auth: g)
Chain Length:154
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:HA (auth: h)
Chain Length:318
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:IA (auth: i)
Chain Length:212
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:JA (auth: j)
Chain Length:108
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:KA (auth: k)
Chain Length:98
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:LA (auth: l)
Chain Length:606
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:MA (auth: m)
Chain Length:129
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:NA (auth: n)
Chain Length:347
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:OA (auth: o)
Chain Length:343
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:PA (auth: p)
Chain Length:380
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:QA (auth: q)
Chain Length:145
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:RA (auth: r)
Chain Length:124
Number of Molecules:1
Biological Source:Bos taurus
Polymer Type:polypeptide(L)
Molecule:NADH dehydrogenase [ubiquinon
Chain IDs:SA (auth: s)
Chain Length:99
Number of Molecules:1
Biological Source:Bos taurus
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
2MR D ARG modified residue
FME A MET modified residue
WYK B ARG modified residue
Ligand Molecules
3PE
CDL
CHD
DGT
EHZ
FES
FMN
K
LMT
MG
MYR
NAI
NDP
PC1
SF4
ZN
Primary Citation
Post-catalysis structures of mitochondrial complex I with ubiquinol-10 bound in the active site.
Nat Commun ? ? ? (2026)
PMID: 41786699 DOI: 10.1038/s41467-026-70030-0
Primary Citation of related structures
9SMH
Feedback Form
Name
Email
Institute
Feedback