ISDA: 9S6S

Deposition Date 2025-08-01

Release Date 2026-03-18

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9S6S

Keywords:

TRANSFERASE

Title:

Ternary cryo-EM structure of human ALG9 with Dol25-PP-GlcNAc2Man6, Dol25-P-Man and Fab

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Homo sapiens, Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.89 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Alpha-1,2-mannosyltransferase
Mutagens:D82A
Chain IDs:A
Chain Length:617
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Hs9-8 Fab heavy chain
Chain IDs:B (auth: H)
Chain Length:240
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polypeptide(L)
Molecule:Hs9-8 Fab light chain
Chain IDs:C (auth: L)
Chain Length:215
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules