ISDA: 9RSD

Deposition Date 2025-07-01

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9RSD

Keywords:

LIGASE

Title:

Ternary complex of a charged molecular glue degrader ZZ1-SO2H, BRD4(BD1) neosubstrate, and the CTLH E3 ligase receptor module YPEL5-WDR26

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Trichoplusia ni, Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.38 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:WD repeat-containing protein
Gene (Uniprot):WDR26
Chain IDs:A (auth: 7), B (auth: W)
Chain Length:645
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9H7D7 Pfam ID:PF17814, PF00400

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Bromodomain-containing protei
Gene (Uniprot):BRD4
Chain IDs:D (auth: B)
Chain Length:130
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O60885 Pfam ID:PF00439

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Protein yippee-like 5
Gene (Uniprot):YPEL5
Chain IDs:C (auth: Y)
Chain Length:121
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62699 Pfam ID:PF03226

Ligand Molecules