9RLZ image
Deposition Date 2025-06-17
Release Date 2026-03-18
Last Version Date 2026-04-01
Entry Detail
PDB ID:
9RLZ
Keywords:
HYDROLASE
Title:
15S proteasome precursor complex
Biological Source:
Source Organism(s):
Saccharomyces cerevisiae (Taxon ID: 4932)
Expression System(s):
Saccharomyces cerevisiae
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.12 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9RLZ validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome maturation factor
Gene (Uniprot):UMP1
Chain IDs:G (auth: 3)
Chain Length:162
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P38293 Pfam ID:PF05348
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome chaperone 1
Gene (Uniprot):PBA1
Chain IDs:H (auth: 4)
Chain Length:276
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:Q05778 Pfam ID:PF10450
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome assembly chaperone
Gene (Uniprot):ADD66
Chain IDs:I (auth: 5)
Chain Length:267
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P36040 Pfam ID:PF09754
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):SCL1
Chain IDs:B (auth: A)
Chain Length:252
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P21243 Pfam ID:PF10584, PF00227 EC:3.4.25.1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PRE8
Chain IDs:J (auth: B)
Chain Length:250
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P23639 Pfam ID:PF10584, PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PRE9
Chain IDs:K (auth: C)
Chain Length:258
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P23638 Pfam ID:PF10584, PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PRE6
Chain IDs:C (auth: D)
Chain Length:254
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P40303 Pfam ID:PF10584, PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PUP2
Chain IDs:D (auth: E)
Chain Length:260
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P32379 Pfam ID:PF10584, PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PRE5
Chain IDs:E (auth: F)
Chain Length:234
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P40302 Pfam ID:PF10584, PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Probable proteasome subunit a
Gene (Uniprot):PRE10
Chain IDs:L (auth: G)
Chain Length:288
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P21242 Pfam ID:PF10584, PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PRE3
Chain IDs:F (auth: H)
Chain Length:215
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P38624 Pfam ID:PF00227 EC:3.4.25.1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PUP1
Chain IDs:M (auth: I)
Chain Length:261
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P25043 Pfam ID:PF00227, PF12465
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PUP3
Chain IDs:N (auth: J)
Chain Length:205
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P25451 Pfam ID:PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PRE1
Chain IDs:O (auth: K)
Chain Length:198
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P22141 Pfam ID:PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PRE2
Chain IDs:P (auth: L)
Chain Length:287
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P30656 Pfam ID:PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PRE7
Chain IDs:A (auth: M)
Chain Length:241
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P23724 Pfam ID:PF00227
Ligand Molecules
NA
Primary Citation
Structural transitions in the stepwise assembly of proteasome core particles.
Nat Commun 17 ? ? (2026)
PMID: 41876489 DOI: 10.1038/s41467-026-70525-w
Primary Citation of related structures
9RLZ
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