ISDA: 9RLA

Deposition Date 2025-06-16

Release Date 2026-03-18

Last Version Date 2026-04-01

Entry Detail

PDB ID:

9RLA

Keywords:

HYDROLASE

Title:

13S+Beta1 proteasome precursor complex

Biological Source:

Source Organism(s):

Saccharomyces cerevisiae (Taxon ID: 4932)

Expression System(s):

Saccharomyces cerevisiae

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.16 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome maturation factor
Gene (Uniprot):UMP1
Chain IDs:F (auth: 3)
Chain Length:162
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P38293 Pfam ID:PF05348

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome chaperone 1
Gene (Uniprot):PBA1
Chain IDs:G (auth: 4)
Chain Length:276
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:Q05778 Pfam ID:PF10450

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome assembly chaperone
Gene (Uniprot):ADD66
Chain IDs:H (auth: 5)
Chain Length:267
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P36040 Pfam ID:PF09754

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):SCL1
Chain IDs:A
Chain Length:252
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P21243 Pfam ID:PF10584, PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PRE8
Chain IDs:I (auth: B)
Chain Length:250
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P23639 Pfam ID:PF10584, PF00227

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PRE9
Chain IDs:J (auth: C)
Chain Length:258
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P23638 Pfam ID:PF10584, PF00227

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PRE6
Chain IDs:B (auth: D)
Chain Length:254
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P40303 Pfam ID:PF10584, PF00227

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PUP2
Chain IDs:C (auth: E)
Chain Length:260
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P32379 Pfam ID:PF10584, PF00227

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PRE5
Chain IDs:D (auth: F)
Chain Length:234
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P40302 Pfam ID:PF10584, PF00227

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Probable proteasome subunit a
Gene (Uniprot):PRE10
Chain IDs:K (auth: G)
Chain Length:288
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P21242 Pfam ID:PF10584, PF00227

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PRE3
Chain IDs:E (auth: H)
Chain Length:215
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P38624 Pfam ID:PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PUP1
Chain IDs:L (auth: I)
Chain Length:261
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P25043 Pfam ID:PF00227, PF12465

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PUP3
Chain IDs:M (auth: J)
Chain Length:205
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P25451 Pfam ID:PF00227

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PRE1
Chain IDs:N (auth: K)
Chain Length:198
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P22141 Pfam ID:PF00227

Ligand Molecules

Primary Citation

Structural transitions in the stepwise assembly of proteasome core particles.

Mark, E, Ramos, P.C, Nunes, M.M, Matias, A.C, Jurgen Dohmen, R, Wendler, P.Show

Nat Commun 17 ? ? (2026)

PMID: 41876489 DOI: 10.1038/s41467-026-70525-w

Primary Citation of related structures

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