9RDK image
Deposition Date 2025-06-03
Release Date 2026-04-01
Last Version Date 2026-04-01
Entry Detail
PDB ID:
9RDK
Keywords:
TRANSCRIPTION
Title:
Cryo-EM structure of the human SAGA co-activator complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.41 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9RDK validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Splicing factor 3B subunit 3
Gene (Uniprot):SF3B3
Chain IDs:D (auth: A)
Chain Length:1217
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q15393 Pfam ID:PF10433, PF23726, PF03178
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Splicing factor 3B subunit 5
Gene (Uniprot):SF3B5
Chain IDs:M (auth: B)
Chain Length:86
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9BWJ5 Pfam ID:PF07189
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transformation/transcription
Gene (Uniprot):TRRAP
Chain IDs:E (auth: C)
Chain Length:3859
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y4A5 Pfam ID:PF20175, PF20206, PF02259, PF00454
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:STAGA complex 65 subunit gamm
Gene (Uniprot):SUPT7L
Chain IDs:F (auth: D)
Chain Length:414
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O94864 Pfam ID:PF07524
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transcription initiation fact
Gene (Uniprot):TAF9B
Chain IDs:A (auth: E)
Chain Length:251
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9HBM6 Pfam ID:PF02291
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transcription initiation fact
Gene (Uniprot):TAF12
Chain IDs:G
Chain Length:161
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q16514 Pfam ID:PF03847
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transcription initiation fact
Gene (Uniprot):TAF10
Chain IDs:H
Chain Length:218
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q12962 Pfam ID:PF03540
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transcription initiation prot
Gene (Uniprot):SUPT3H
Chain IDs:I
Chain Length:317
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O75486 Pfam ID:PF02269
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transcriptional adapter 1
Gene (Uniprot):TADA1
Chain IDs:J
Chain Length:335
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q96BN2 Pfam ID:PF12767
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:TAF6-like RNA polymerase II p
Gene (Uniprot):TAF6L
Chain IDs:K
Chain Length:622
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y6J9 Pfam ID:PF02969, PF07571
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:TAF5-like RNA polymerase II p
Gene (Uniprot):TAF5L
Chain IDs:C (auth: L)
Chain Length:589
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O75529 Pfam ID:PF04494, PF00400
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transcription factor SPT20 ho
Gene (Uniprot):SUPT20H
Chain IDs:L (auth: M)
Chain Length:779
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q8NEM7 Pfam ID:PF12090
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ataxin-7
Gene (Uniprot):ATXN7
Chain IDs:B (auth: N)
Chain Length:892
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O15265 Pfam ID:PF08313
Ligand Molecules
NA
Primary Citation
Insights into the structure and evolution of the human SAGA complex by affinity-ligand purification.
Sci Adv 12 eaec8104 eaec8104 (2026)
PMID: 41849588 DOI: 10.1126/sciadv.aec8104
Primary Citation of related structures
9RDK
Feedback Form
Name
Email
Institute
Feedback