ISDA: 9RB8

Deposition Date 2025-05-21

Release Date 2026-03-11

Last Version Date 2026-03-11

Entry Detail

PDB ID:

9RB8

Keywords:

PROTEIN FIBRIL

Title:

Wild-type alpha-synuclein fibril - Type 3-1

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.64 Å

Aggregation State:

FILAMENT

Reconstruction Method:

HELICAL

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Alpha-synuclein
Gene (Uniprot):SNCA
Chain IDs:A, B, C, D, E, F, G, H, I, J
Chain Length:140
Number of Molecules:10
Biological Source:Homo sapiens

UniProt ID:P37840 Pfam ID:PF01387

Ligand Molecules

Primary Citation

Stochastic misfolding drives the emergence of distinct alpha-synuclein strains.

So, R.W.L, Frieg, B, Camino, J.D, Situ, C, Metri, M.N, Silver, N.R.G, Li, L.Y, Mao, A, Stuart, E, Schroder, G.F, Watts, J.C.Show

Neuron ? ? ? (2026)

PMID: 41763203 DOI: 10.1016/j.neuron.2026.01.014

Primary Citation of related structures

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