9QPP image
Deposition Date 2025-03-27
Release Date 2026-04-08
Last Version Date 2026-04-08
Entry Detail
PDB ID:
9QPP
Keywords:
TRANSFERASE
Title:
CryoEM structure of human MATa2 in complex with MAT2B isoform v1 at 2.6 A resolution
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli, Escherichia coli bl21
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.60 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9QPP validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:S-adenosylmethionine synthase
Gene (Uniprot):MAT2A
Chain IDs:A (auth: B), C (auth: A), D (auth: C), E (auth: D)
Chain Length:395
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:P31153 Pfam ID:PF00438, PF02772, PF02773 EC:2.5.1.6
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Methionine adenosyltransferas
Gene (Uniprot):MAT2B
Mutagens:NONE
Chain IDs:B (auth: E), F, G
Chain Length:334
Number of Molecules:3
Biological Source:Homo sapiens
UniProt ID:Q9NZL9 Pfam ID:PF04321 EC:2.5.1.6
Primary Citation
High resolution cryoEM structures reveal allosteric regulation of the catalytic activity of the multi-protein human MAT enzyme complexes
To Be Published ? ? ? (?)
Primary Citation of related structures
9QPP
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