ISDA: 9QPM

Deposition Date 2025-03-27

Release Date 2026-03-25

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9QPM

Keywords:

MEMBRANE PROTEIN

Title:

BtuJ1 (BT_1491) bound to cyanocobalamin

Biological Source:

Source Organism(s):

Bacteroides thetaiotaomicron VPI-5482 (Taxon ID: 226186)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.40 Å

R-Value Free:

0.19

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

P 2 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DUF4465 domain-containing pro
Gene (Uniprot):BT_1491
Chain IDs:A
Chain Length:244
Number of Molecules:1
Biological Source:Bacteroides thetaiotaomicron VPI-5482

UniProt ID:Q8A7N3 Pfam ID:PF14717

Ligand Molecules

CNC

Primary Citation

BtuJ1, a Surface-exposed B 12 -binding Protein in Bacteroidota, Functions as an Extracellular Vitamin Reservoir That Enhances Fitness.

Abellon-Ruiz, J, Pacheco-Gomez, R, Watts, J, Hart, A, Hirt, R.P, Basle, A, van den Berg, B, Liebschner, D, Afonine, P.V, Baker, M.L, Bunkoczi, G, Chen, V.B, Croll, T.I, Hintze, B, Hung, L.W, Jain, S, McCoy, A.J, Moriarty, N.W, Oeffner, R.D, Poon, B.K, Prisant, M.G, Read, R.J, Richardson, J.S, Richardson, D.C, Sammito, M.D, Sobolev, O.V, Stockwell, D.H, Terwilliger, T.C, Urzhumtsev, A.G, Videau, L.L, Williams, C.J, Adams, P.D.Show

J.Mol.Biol. 438 169754 169754 (2026)

PMID: 41831674 DOI: 10.1016/j.jmb.2026.169754

Primary Citation of related structures

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