ISDA: 9QOY

Deposition Date 2025-03-26

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9QOY

Keywords:

ANTIMICROBIAL PROTEIN

Title:

Pseudomonas aeruginosa APH(3")-IIb - Wild Type

Biological Source:

Source Organism(s):

Pseudomonas aeruginosa (Taxon ID: 287)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.79 Å

R-Value Free:

0.22

R-Value Work:

0.18

Space Group:

C 2 2 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Aminoglycoside 3'-phosphotran
Gene (Uniprot):aph
Chain IDs:A, B
Chain Length:288
Number of Molecules:2
Biological Source:Pseudomonas aeruginosa

UniProt ID:Q9HWR2 Pfam ID:PF01636

Ligand Molecules

Primary Citation

Structural and molecular basis of resistance to aminoglycoside antibiotics by APH(3')IIb from Pseudomonas aeruginosa

Kowalewski, J, Tomaszczyk, M, Guichou, J.F, Gelin, M, Labesse, G, Lionne, C, Liebschner, D, Afonine, P.V, Baker, M.L, Bunkoczi, G, Chen, V.B, Croll, T.I, Hintze, B, Hung, L.W, Jain, S, McCoy, A.J, Moriarty, N.W, Oeffner, R.D, Poon, B.K, Prisant, M.G, Read, R.J, Richardson, J.S, Richardson, D.C, Sammito, M.D, Sobolev, O.V, Stockwell, D.H, Terwilliger, T.C, Urzhumtsev, A.G, Videau, L.L, Williams, C.J, Adams, P.D.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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