ISDA: 9QDY

Deposition Date 2025-03-07

Release Date 2026-03-18

Last Version Date 2026-03-18

Entry Detail

PDB ID:

9QDY

Keywords:

LIGASE

Title:

GID4 in complex with Compound 9

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.10 Å

R-Value Free:

0.25

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Glucose-induced degradation p
Gene (Uniprot):GID4
Chain IDs:A
Chain Length:166
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q8IVV7 Pfam ID:PF09783

Ligand Molecules

A1I6B

Primary Citation

Novel chemical probes and conformational flexibility of GID4 - a substrate receptor of the Human CTLH E3 ligase complex

Skowron, A.N, Gorecka-Minakowska, K.M, Klejnot, M, Pastok, M.W, Wisniewski, J, Walczak, M.J.Show

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