ISDA: 9PE0

Deposition Date 2025-07-01

Release Date 2026-03-25

Last Version Date 2026-03-25

Entry Detail

PDB ID:

9PE0

Keywords:

IMMUNE SYSTEM

Title:

CryoEM structure of the GSDME pore, C27

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.64 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Gasdermin-E, N-terminal
Gene (Uniprot):GSDME
Chain IDs:A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, AA (auth: a)
Chain Length:270
Number of Molecules:27
Biological Source:Homo sapiens

UniProt ID:O60443 Pfam ID:PF04598

Ligand Molecules

Primary Citation

CryoEM structure of the GSDME pore, C27 symmetry

Teran, E, Ni, D.C, Wang, C.W, Ruan, J.B.Show

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