ISDA: 9P6S

Deposition Date 2025-06-19

Release Date 2026-03-25

Last Version Date 2026-03-25

Entry Detail

PDB ID:

9P6S

Keywords:

CELL ADHESION

Title:

Cryo-EM structure of human integrin alpha5beta1 in complex with fibronectin (FN 7-10)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.61 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Integrin alpha-5
Gene (Uniprot):ITGA5
Chain IDs:A
Chain Length:601
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P08648 Pfam ID:PF01839, PF08441

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Integrin beta-1
Gene (Uniprot):ITGB1
Chain IDs:B
Chain Length:440
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P05556 Pfam ID:PF17205, PF00362

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Fibronectin
Gene (Uniprot):FN1
Chain IDs:C
Chain Length:183
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P02751 Pfam ID:PF00041

Ligand Molecules