ISDA: 9OZD

Deposition Date 2025-06-05

Release Date 2026-03-11

Last Version Date 2026-03-25

Entry Detail

PDB ID:

9OZD

Keywords:

LYASE

Title:

Crystal structure of the polysaccharide lyase RbmB from Vibrio cholerae bound to Vibrio Polysaccharide

Biological Source:

Source Organism(s):

Vibrio cholerae (Taxon ID: 948564)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.62 Å

R-Value Free:

0.20

R-Value Work:

0.16

R-Value Observed:

0.16

Space Group:

P 1 21 1

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Polysaccharide lyase
Chain IDs:A, B, C, D
Chain Length:380
Number of Molecules:4
Biological Source:Vibrio cholerae

Ligand Molecules

FMT

GOL

Primary Citation

Crystal structure of Vibrio cholerae polysaccharide lyase RbmB bound to Vibrio polysaccharide (VPS) fragments provides insights into substrate recognition and cleavage.

Weerasekera, R, Moreau, A, Huang, X, Potapova, A, Schwechheimer, C, Kandel, R, Huynh, Y, Cannizzo, O, Gordon, R, Gerace, E, Hinbest, A.J, Yang, Y, Jiang, X, Woods, R.J, Yan, J, Yildiz, F.H, Olson, R, Weerasekera, R, Moreau, A, Huang, X, Nam, K.M, Hinbest, A.J, Huynh, Y, Liu, X, Ashwood, C, Pepi, L.E, Paulson, E, Cegelski, L, Yan, J, Olson, R.Show

Proc.Natl.Acad.Sci.USA 123 e2534280123 e2534280123 (2026)

PMID: 41805565 DOI: 10.1073/pnas.2534280123

Primary Citation of related structures

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