9OZC image
Deposition Date 2025-06-05
Release Date 2026-02-25
Last Version Date 2026-04-08
Entry Detail
PDB ID:
9OZC
Keywords:
SIGNALING PROTEIN
Title:
Cryo-EM structure of 1:2:1 ROS1/NEL/NICOL holo-complex, conformation 1.
Biological Source:
Source Organism(s):
Gallus gallus (Taxon ID: 9031)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
4.00 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9OZC validation report
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Tyrosine-protein kinase recep
Chain IDs:A
Chain Length:2311
Number of Molecules:1
Biological Source:Gallus gallus
Polymer Type:polypeptide(L)
Molecule:Protein NEL
Chain IDs:B, C
Chain Length:816
Number of Molecules:2
Biological Source:Gallus gallus
Polymer Type:polypeptide(L)
Molecule:NELL2-interacting cell ontoge
Chain IDs:D
Chain Length:95
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
NAG
Primary Citation
Structural insights into the activation of the chicken ROS1 receptor by the NEL/NICOL ligand complex.
Nat Commun 17 ? ? (2026)
PMID: 41735298 DOI: 10.1038/s41467-026-69942-8
Primary Citation of related structures
9OZC
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