9OJM image
Deposition Date 2025-05-08
Release Date 2026-03-18
Last Version Date 2026-03-18
Entry Detail
PDB ID:
9OJM
Keywords:
RIBOSOME
Title:
Human mitochondrial 28S PIC with tRNA and mtIF2
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.50 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9OJM validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS34
Chain IDs:A (auth: 0)
Chain Length:215
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82930 Pfam ID:PF16053
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS35
Chain IDs:B (auth: 1)
Chain Length:278
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82673 Pfam ID:PF10213
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Coiled-coil-helix-coiled-coil
Gene (Uniprot):CHCHD1
Chain IDs:C (auth: 2)
Chain Length:118
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q96BP2 Pfam ID:PF06747
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):AURKAIP1
Chain IDs:D (auth: 3)
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9NWT8 Pfam ID:PF08213
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):PTCD3
Chain IDs:E (auth: 4)
Chain Length:616
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q96EY7 Pfam ID:PF22330, PF13812
Polymer Type:polyribonucleotide
Molecule:RNA (71-MER)
Chain IDs:F (auth: 5)
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polyribonucleotide
Molecule:mRNA (5'-R(P*AP*UP*GP*U)-3')
Chain IDs:G (auth: 6)
Chain Length:4
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Translation initiation factor
Gene (Uniprot):MTIF2
Chain IDs:H (auth: 7)
Chain Length:571
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P46199 Pfam ID:PF00009, PF22042, PF11987
Polymer Type:polyribonucleotide
Molecule:12S mitochondrial RNA
Chain IDs:I (auth: A)
Chain Length:955
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS2
Chain IDs:J (auth: B)
Chain Length:225
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y399 Pfam ID:PF00318
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S24, mi
Gene (Uniprot):MRPS24
Chain IDs:K (auth: C)
Chain Length:132
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q96EL2 Pfam ID:PF14955
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S5, mit
Gene (Uniprot):MRPS5
Chain IDs:L (auth: D)
Chain Length:343
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82675 Pfam ID:PF21251, PF00333, PF03719
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S6, mit
Gene (Uniprot):MRPS6
Chain IDs:M (auth: E)
Chain Length:122
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82932 Pfam ID:PF01250
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S7, mit
Gene (Uniprot):MRPS7
Chain IDs:N (auth: F)
Chain Length:208
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y2R9 Pfam ID:PF00177
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS9
Chain IDs:O (auth: G)
Chain Length:344
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82933 Pfam ID:PF00380
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS10
Chain IDs:P (auth: H)
Chain Length:140
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82664 Pfam ID:PF00338
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS11
Chain IDs:Q (auth: I)
Chain Length:137
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82912 Pfam ID:PF00411
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S12, mi
Gene (Uniprot):MRPS12
Chain IDs:R (auth: J)
Chain Length:108
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O15235 Pfam ID:PF00164
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S14, mi
Gene (Uniprot):MRPS14
Chain IDs:S (auth: K)
Chain Length:101
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O60783 Pfam ID:PF00253
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS15
Chain IDs:T (auth: L)
Chain Length:174
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82914 Pfam ID:PF00312
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS16
Chain IDs:U (auth: M)
Chain Length:119
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y3D3 Pfam ID:PF00886
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS17
Chain IDs:V (auth: N)
Chain Length:110
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y2R5 Pfam ID:PF00366
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S18b, m
Chain IDs:W (auth: O)
Chain Length:193
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S18c, m
Chain IDs:X (auth: P)
Chain Length:97
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S21, mi
Gene (Uniprot):MRPS21
Chain IDs:Y (auth: Q)
Chain Length:87
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82921 Pfam ID:PF01165
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS22
Chain IDs:Z (auth: R)
Chain Length:295
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82650 Pfam ID:PF10245
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S23, mi
Chain IDs:AA (auth: S)
Chain Length:135
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS25
Chain IDs:BA (auth: T)
Chain Length:168
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82663 Pfam ID:PF05047
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS26
Chain IDs:CA (auth: U)
Chain Length:176
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9BYN8 Pfam ID:PF14943
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS27
Chain IDs:DA (auth: V)
Chain Length:379
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q92552 Pfam ID:PF10037
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS28
Chain IDs:EA (auth: W)
Chain Length:100
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y2Q9 Pfam ID:PF10246
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):DAP3
Chain IDs:FA (auth: X)
Chain Length:352
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P51398 Pfam ID:PF10236
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S27, mi
Chain IDs:GA (auth: Y)
Chain Length:149
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):MRPS33
Chain IDs:HA (auth: Z)
Chain Length:100
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y291 Pfam ID:PF08293
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
5MC I C modified residue
5MU I U modified residue
B8T I C modified residue
MA6 I A modified residue
Ligand Molecules
ATP
FES
GDP
GTP
K
MG
ZN
Primary Citation
Mechanisms of human mitochondrial leaderless mRNA translation initiation
Nat Commun ? ? ? (2026)
Primary Citation of related structures
9OJM
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